Cain is the first son of Adam and Eve in the Bible.
Cain may also refer to:
People
- Cain (surname)
- Cain Madden (born 1996), American football player
- Cain Velasquez (born 1982), Mexican American mixed martial arts fighter and 2010 UFC Heavyweight Champion
Arts and entertainment
Fictional characters
- Cain, the decoy assassin in Robert Ludlum's The Bourne Identity
- Cain, the Green Planet mage from The King of Braves GaoGaiGar
- Cain, main antagonist from the 1990 film RoboCop 2
- Cain and Abel (comics), most notably seen in The Sandman series and House of Mystery
- Cain C. Hargreaves, a character from Kaori Yuki's manga: Godchild
- Cain Dingle, Emmerdale character
- Cain Marko, name of the Marvel character Juggernaut
- Cassandra Cain, name of the DC Comics character Batgirl
- Ciaphas Cain, character from the Warhammer 40,000 universe
- Cogliostro, born as Cain, brother and killer of Abel, a supporting character in Todd McFarlane's Spawn comic series
- Commander Cain, of the Battlestar Pegasus in Battlestar Galactica
- David Cain (character), father of the DC Comics character Batgirl/Cassandra Cain
- Strider Cain, a character from the Strider franchise; See Strider Hiryu
Other arts and entertainment
- Cain (American band), an American Christian country band
- Cain (Italian band), an Italian black metal band
- Cain (novel), the final novel by Nobel Prize-winning author José Saramago
- Cain (play), an 1821 play by Lord Byron
- Cain (1918 film), a German silent film
- Caín (film), a 1984 Colombian drama directed by Gustavo Nieto Roa
Other uses
- Cain (software), network packet analyzing software
- Conflict Archive on the Internet (CAIN), a website documenting the Troubles in Northern Ireland
- Mount Cain, Vancouver Island, British Columbia, Canada
- Cain's Ballroom, a music venue in Tulsa, Oklahoma, US
- Cain, a cigar brand made by Oliva Cigar Co.