Pseudomonas aeruginosa: Difference between revisions

Medical-Grade honey (i.e., containing Unique Manuka Factor) may reduce colonization of many pathogens including ''Pseudomonas aeruginosa''.<ref>Kwakman PH, Van den Akker JP, Güçlü A, Aslami H, Binnekade JM, de Boer L, Boszhard L, Paulus F, Middelhoek P, te Velde AA, Vandenbroucke-Grauls CM, Schultz MJ, Zaat SA. Medical-grade honey kills antibiotic-resistant bacteria in vitro and eradicates skin colonization.Clin Infect Dis. 2008 Jun 1;46(11):1677-82.</ref> Probiotic prophylaxis may prevent colonization and delay onset of pseudomonas infection in an ICU setting.<ref>Forestier C, Guelon D, Cluytens V, Gillart T, Sirot J, de Champs C. Oral probiotic and prevention of Pseudomonas aeruginosa infections: a randomized, double-blind, placebo-controlled pilot study in ICU-patients.Crit Care. 2008 May 19;12(3):R69.</ref> Immunoprophylaxis against pseudomonas is being investigated. <ref>{{cite journal|author=Döring G, Pier GB|title=Vaccines and immunotherapy against ''Pseudomonas aeruginosa''|journal=Vaccine|year=2008|volume=26|issue=8|pages=1011&ndash;24|pmid=18242792}}</ref>

Most recently, a Brazilian model named [[Mariana Bridi da Costa]] had her hands and feet both amputated due to ''Pseudomonas aeruginosa'' that presented itself as a [[urinary tract infection]]. In early January, she went into [[septic shock]] due to the infection, and later had both hands and feet amputated in an effort to save her life. Bridi lived only a few days after the amputations and died on January 24, 2009 at 2:30 am. The doctors that treated Bridi attribute her death to complications with the generalized infection and the subsequent surgery. She was 20 years old at the time of her death.<ref>["Model Who Lost Hands, Feet Dies", Associated Press via Yahoo News (January 24 2009)]</ref>