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Line 1: {{Orphan|date=January 2016}} {{expert needed| '''Microtubule plus-end/positive-end tracking proteins''' or '''+TIPs''' are a type of [[Microtubule-associated protein|microtubule associated protein (MAP)]] which accumulate at the plus ends of [[microtubules]]. +TIPs are arranged in diverse groups which are classified based on their structural components; however, all classifications are distinguished by their specific accumulation at the plus end of microtubules and their ability to maintain interactions between themselves and other +TIPs regardless of type. +TIPs can be either membrane bound or cytoplasmic, depending on the type of +TIPs. Most +TIPs track the ends of extending microtubules in a non-autonomous manner.[[File:MTB-3-a-Microtubule-Plus-End-Tracking-Protein-(+TIP)-of-Neurospora-crassa-pone.0070655.s006.ogv|thumb|MTB Microtubule Plus End Tracking Protein (+TIP) of Neurospora crassa-pone.{{clarify|date=December 2015}}]] |
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