Defending champion Esther Vergeer defeated Yana Buchina in the final, 6–1, 6–2 to win the women's singles wheelchair tennis title at the 2006 US Open.
| Wheelchair women's singles | |
|---|---|
| 2006 US Open | |
| Champion |  Esther Vergeer |
| Runner-up | Sharon Walraven |
| Score | 6-1, 6-2 |
Draw
Key
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- SE = Special exempt
- PR = Protected ranking
- ITF = ITF entry
- JE = Junior exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
- SR = Special ranking
Finals
| First round | Semifinals | Final | ||||||||||||||||||
| Esther Vergeer | 6 | 6 | ||||||||||||||||||
 Kaitlyn Verfuerth | 1 | 1 | ||||||||||||||||||
| Esther Vergeer | 6 | 6 | ||||||||||||||||||
| Maaike Smit | 1 | 2 | ||||||||||||||||||
| Beth Arnoult-Ritthaler | 0 | 1 | ||||||||||||||||||
| Maaike Smit | 6 | 6 | ||||||||||||||||||
| Esther Vergeer | 6 | 6 | ||||||||||||||||||
| Sharon Walraven | 1 | 2 | ||||||||||||||||||
| Sharon Walraven | 6 | 6 | ||||||||||||||||||
| Jiske Griffioen | 4 | 2 | ||||||||||||||||||
| Sharon Walraven | 7 | 5 | 6 | |||||||||||||||||
| Korie Homan | 61 | 7 | 1 | |||||||||||||||||
| Korie Homan | 7 | 3 | 6 | |||||||||||||||||
 Florence Gravellier | 5 | 6 | 3 | |||||||||||||||||
References
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