The 5th Guard Grenadiers (German: Garde-Grenadier-Regiment Nr. 5) was a regiment of the Prussian Army prior to and during the First World War. Established in 1897, it was part of the 5th Guard Infantry Brigade. The regiment was disbanded following the war and perpetuated by 5th and 6th Company, 4th Infantry Regiment of the Reichswehr.
| 5th Guards Grenadiers | |
|---|---|
| Garde-Grenadier-Regiment Nr. 5 | |
 A memorial to the soldiers of the regiment in Spandau | |
| Active | 31 March 1897–12 December 1918 |
| Disbanded | 12 December 1918 |
| Country | German Empire |
| Allegiance | Kingdom of Prussia |
| Branch | Infantry |
| Type | Grenadiers |
| Part of | Guards Corps |
| Garrison/HQ | Spandau |
| Nickname(s) | Briefträger (post men) |
| Commanders | |
| Ceremonial chief | Grand Duke Konstantin Konstantinovich of Russia |
| Notable commanders |
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