ABCF2

ABCF2
Identifiers
Aliases	ABCF2, ABC28, EST133090, HUSSY18, HUSSY-18, ATP binding cassette subfamily F member 2
External IDs	OMIM: 612510; MGI: 1351657; HomoloGene: 21408; GeneCards: ABCF2; OMA:ABCF2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	151,227,205 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	24,782,465 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; gastrocnemius muscle; ; tibialis anterior muscle; ; endothelial cell; ; secondary oocyte; ; prefrontal cortex; ; Brodmann area 9; ; left ventricle; ; deltoid muscle; ; stromal cell of endometrium;
	Top expressed in
	spermatid; ; spermatocyte; ; morula; ; seminiferous tubule; ; somite; ; superior frontal gyrus; ; maxillary prominence; ; lip; ; secondary oocyte; ; primitive streak;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; ATPase activity; ATP binding; transporter activity;
Cellular component	ATP-binding cassette (ABC) transporter complex; mitochondrial envelope; membrane; mitochondrion;
Biological process	transport;
	Sources:Amigo / QuickGO
Orthologs
	10061
	27407
	ENSG00000033050
	ENSMUSG00000028953
	Q9UG63
	Q99LE6
	NM_007189
	NM_001190443; NM_013853; NM_001359205
	NP_005683; NP_009120
	NP_001177372; NP_038881; NP_001346134
	Wikidata
View/Edit Human	View/Edit Mouse

ATP-binding cassette sub-family F member 2 is a protein that in humans is encoded by the ABCF2 gene.^[5]^[6]

Function

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This protein is a member of the GCN20 subfamily. Alternative splicing of this gene results in multiple transcript variants.^[6]

ABCF2 acts as a suppressor of the volume-sensitive outwardly rectifying Cl channel (CLCN3).^[7]

References

External links

ABCF2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
ABCF2 human gene location in the UCSC Genome Browser.
ABCF2 human gene details in the UCSC Genome Browser.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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ABCF2

Contents

Function

See also

References

Further reading

External links