| Autoantibody | |
|---|---|
| Anti-p62 | |
| Autoantigen Isoform | Nucleoporin 62kDA |
| Autoantigen gene | NUP62 |
| Affected organ(s) | Bile duct |
| Associated Disease(s) | Primary biliary cirrhosis |
| HLA associations | DR2 (weak) |
Anti-p62 antibodies (AP62A) are found in a primary biliary cirrhosis.[1] The p62 protein is also more frequent in Stage IV primary biliary cirrhosis and is prognostic for severe disease.[2][3] The autoantigen is the nucleoporin 62kDA protein.
References
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