The Autostrada A21 is an Italian motorway, which connects Turin to Brescia, through the Po Valley and the city of Piacenza.
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| Autostrada dei Vini | |
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| Route information | |
| Maintained by ANAS | |
| Length | 238.3 km (148.1 mi) |
| Existed | 1968–present |
| Major junctions | |
| West end | Turin |
| East end | Brescia |
| Location | |
| Country | Italy |
| Regions | Piedmont – Emilia-Romagna – Lombardy |
| Highway system | |