CHMP2A

Charged multivesicular body protein 2a is a protein that in humans is encoded by the CHMP2A gene.^[5][6][7]

CHMP2A
Identifiers
Aliases	CHMP2A, BC-2, BC2, CHMP2, VPS2, VPS2A, charged multivesicular body protein 2A
External IDs	OMIM: 610893; MGI: 1916203; HomoloGene: 6382; GeneCards: CHMP2A; OMA:CHMP2A - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.43 Start 58,551,452 bp[1] End 58,555,105 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 A1|7 Start 12,765,937 bp[2] End 12,768,734 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right adrenal gland left adrenal gland oral cavity gastric mucosa body of stomach skin of abdomen monocyte caudate nucleus left coronary artery nucleus accumbens Top expressed in corneal stroma saccule seminal vesicula superior surface of tongue arcuate nucleus olfactory epithelium left colon right lung lobe lip epithelium of stomach More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein domain specific binding phosphatidylcholine binding protein binding Cellular component cytosol endosome membrane late endosome membrane membrane coat extracellular exosome ESCRT III complex nuclear envelope chromatin multivesicular body Biological process regulation of centrosome duplication protein polymerization viral budding via host ESCRT complex protein heterooligomerization nucleus organization viral life cycle establishment of protein localization negative regulation of centriole elongation membrane invagination multivesicular body assembly negative regulation of cell death regulation of mitotic spindle assembly endosomal transport transport protein transport positive regulation of exosomal secretion septum digestion after cytokinesis mitotic metaphase plate congression protein homooligomerization vacuolar transport regulation of viral process ESCRT III complex disassembly nuclear membrane reassembly exit from mitosis macroautophagy endosome transport via multivesicular body sorting pathway late endosome to vacuole transport midbody abscission Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 27243 68953 Ensembl ENSG00000130724 ENSMUSG00000033916 UniProt O43633 Q9DB34 RefSeq (mRNA) NM_014453 NM_198426 NM_026885 NM_001360730 NM_001360731 NM_001360733 RefSeq (protein) NP_055268 NP_940818 NP_081161 NP_001347659 NP_001347660 NP_001347662 Location (UCSC) Chr 19: 58.55 – 58.56 Mb Chr 7: 12.77 – 12.77 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

It is a reference gene.