CHMP4C

Charged multivesicular body protein 4c is a protein that in humans is encoded by the CHMP4C gene.^[5][6][7]

CHMP4C
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3C3R
Identifiers
Aliases	CHMP4C, SNF7-3, Shax3, VPS32C, charged multivesicular body protein 4C
External IDs	OMIM: 610899; MGI: 1913621; HomoloGene: 23544; GeneCards: CHMP4C; OMA:CHMP4C - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q21.13 Start 81,732,448 bp[1] End 81,759,515 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 A1 Start 10,431,967 bp[2] End 10,493,916 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in amniotic fluid jejunal mucosa palpebral conjunctiva parotid gland duodenum pancreatic epithelial cell body of pancreas oral cavity skin of abdomen islet of Langerhans Top expressed in interventricular septum ileum duodenum jejunum epithelium of stomach Paneth cell left colon ascending aorta parotid gland aortic valve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein homodimerization activity protein binding Cellular component cytoplasm ESCRT III complex cytosol endosome membrane late endosome membrane midbody Flemming body Biological process regulation of centrosome duplication abscission viral budding via host ESCRT complex viral life cycle nucleus organization multivesicular body assembly regulation of mitotic spindle assembly endosomal transport ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway protein transport negative regulation of cytokinesis septum digestion after cytokinesis mitotic metaphase plate congression vacuolar transport macroautophagy mitotic cytokinesis checkpoint signaling midbody abscission Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 92421 66371 Ensembl ENSG00000164695 ENSMUSG00000027536 UniProt Q96CF2 Q9D7F7 RefSeq (mRNA) NM_152284 NM_025519 RefSeq (protein) NP_689497 NP_079795 Location (UCSC) Chr 8: 81.73 – 81.76 Mb Chr 3: 10.43 – 10.49 Mb PubMed search [3] [4]
Wikidata
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