CREBRF

CREB3 regulatory factor is a protein that in humans is encoded by the CREBRF gene.^[5]

CREBRF
Identifiers
Aliases	CREBRF, C5orf41, LRF, CREB3 regulatory factor
External IDs	OMIM: 617109; MGI: 1924378; HomoloGene: 12672; GeneCards: CREBRF; OMA:CREBRF - orthologs
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q35.1 Start 173,056,352 bp[1] End 173,139,284 bp[1]
Gene location (Mouse) Chr. Chromosome 17 (mouse)[2] Band 17|17 A3.3 Start 26,715,650 bp[2] End 26,776,635 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon superficial temporal artery synovial membrane internal globus pallidus lower lobe of lung urethra bone marrow cells cardiac muscle tissue of right atrium caput epididymis tail of epididymis Top expressed in ciliary body spermatocyte dorsomedial hypothalamic nucleus iris carotid body spermatid retinal pigment epithelium suprachiasmatic nucleus habenula substantia nigra More reference expression data BioGPS n/a
Gene ontology Molecular function DNA-binding transcription factor activity protein binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component cytoplasm nuclear body nucleus nucleoplasm Biological process negative regulation of endoplasmic reticulum unfolded protein response positive regulation of prolactin signaling pathway response to unfolded protein regulation of transcription, DNA-templated negative regulation of transcription by RNA polymerase II positive regulation of protein catabolic process maternal behavior negative regulation of glucocorticoid mediated signaling pathway positive regulation of intracellular transport transcription, DNA-templated response to endoplasmic reticulum stress positive regulation of protein transport endoplasmic reticulum unfolded protein response transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 153222 77128 Ensembl ENSG00000164463 ENSMUSG00000048249 UniProt Q8IUR6 Q8CDG5 RefSeq (mRNA) NM_001168393 NM_001168394 NM_153607 NM_029870 RefSeq (protein) NP_001161865 NP_001161866 NP_705835 NP_084146 Location (UCSC) Chr 5: 173.06 – 173.14 Mb Chr 17: 26.72 – 26.78 Mb PubMed search [3] [4]
Wikidata
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