Cloflubicyne

Cloflubicyne
Names
	IUPAC name 5,6-dichloro-3,3-bis(trifluoromethyl)bicyclo[2.2.1]heptane-2,2-dicarbonitrile
Identifiers
CAS Number	224790-70-9;
3D model (JSmol)	Interactive image;
ChemSpider	2328106;
PubChem CID	5067794;
CompTox Dashboard (EPA)	DTXSID80274166 ;
	InChI InChI=1S/C11H6Cl2F6N2/c12-6-4-1-5(7(6)13)9(10(14,15)16,11(17,18)19)8(4,2-20)3-21/h4-7H,1H2 Key: NTESZNJQNKSALM-UHFFFAOYSA-N;
	SMILES C1C2C(C(C1C(C2(C#N)C#N)(C(F)(F)F)C(F)(F)F)Cl)Cl;
Properties
Chemical formula	C11H6Cl2F6N2
Molar mass	351.07 g·mol−1
Hazards
	Occupational safety and health (OHS/OSH):
Main hazards	Extremely toxic
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	0.1 mg/kg (intraperitoneal, mice)
LDLo (lowest published)	0.2 mg/kg (oral, rats)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Cloflubicyne is a chemical compound which is a chlorinated derivative of BIDN. It is an irreversible GABA receptor antagonist with powerful convulsant effects.^[3]^[4]^[5]^[6]

References

Names

IUPAC name 5,6-dichloro-3,3-bis(trifluoromethyl)bicyclo[2.2.1]heptane-2,2-dicarbonitrile
Identifiers
CAS Number	224790-70-9
3D model (JSmol)	Interactive image
ChemSpider	2328106
PubChem CID	5067794
CompTox Dashboard (EPA)	DTXSID80274166
InChI InChI=1S/C11H6Cl2F6N2/c12-6-4-1-5(7(6)13)9(10(14,15)16,11(17,18)19)8(4,2-20)3-21/h4-7H,1H2 Key: NTESZNJQNKSALM-UHFFFAOYSA-N
SMILES C1C2C(C(C1C(C2(C#N)C#N)(C(F)(F)F)C(F)(F)F)Cl)Cl
Properties
Chemical formula	C₁₁H₆Cl₂F₆N₂
Molar mass	351.07 g·mol⁻¹
Hazards
Occupational safety and health (OHS/OSH):
Main hazards	Extremely toxic
Lethal dose or concentration (LD, LC):
LD₅₀ (median dose)	0.1 mg/kg (intraperitoneal, mice)^[1]
LD_Lo (lowest published)	0.2 mg/kg (oral, rats)^[2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references