Dicentrine

Dicentrine
Names
	Preferred IUPAC name (7aS)-10,11-Dimethoxy-7-methyl-6,7,7a,8-tetrahydro-2H,5H-benzo[g][1,3]benzodioxolo[6,5,4-de]quinoline
	Other names (S)-(+)-Dicentrine
Identifiers
CAS Number	517-66-8 ;
3D model (JSmol)	Interactive image;
ChemSpider	91532;
PubChem CID	101300;
UNII	J2ZGT5M0N7 ;
CompTox Dashboard (EPA)	DTXSID10199651 ;
	InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17-20(25-10-24-17)19-13-9-16(23-3)15(22-2)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1 Key: YJWBWQWUHVXPNC-AWEZNQCLSA-N;
	SMILES CN1CCc2cc3c(c-4c2[C@@H]1Cc5c4cc(c(c5)OC)OC)OCO3;
Properties
Chemical formula	C20H21NO4
Molar mass	339.391 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Dicentrine is an aporphinic alkaloid found in several plant species, mainly from family Lauraceae, including Lindera megaphylla.^[1] At high doses, dicentrine shows antinociceptive activity in a mouse model of pain.^[2] It probably acts via a TRPA1-dependent mechanism.^[2]

References

[1]

[2]

Names

Preferred IUPAC name (7aS)-10,11-Dimethoxy-7-methyl-6,7,7a,8-tetrahydro-2H,5H-benzo[g][1,3]benzodioxolo[6,5,4-de]quinoline
Other names (S)-(+)-Dicentrine
Identifiers
CAS Number	517-66-8^Y
3D model (JSmol)	Interactive image
ChemSpider	91532
PubChem CID	101300
UNII	J2ZGT5M0N7^Y
CompTox Dashboard (EPA)	DTXSID10199651
InChI InChI=1S/C20H21NO4/c1-21-5-4-11-7-17-20(25-10-24-17)19-13-9-16(23-3)15(22-2)8-12(13)6-14(21)18(11)19/h7-9,14H,4-6,10H2,1-3H3/t14-/m0/s1 Key: YJWBWQWUHVXPNC-AWEZNQCLSA-N
SMILES CN1CCc2cc3c(c-4c2[C@@H]1Cc5c4cc(c(c5)OC)OC)OCO3
Properties
Chemical formula	C₂₀H₂₁NO₄
Molar mass	339.391 g·mol⁻¹
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references