Famprofazone

Famprofazone
Clinical data
Routes of; administration	Oral
ATC code	none;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 1-methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-4-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one;
CAS Number	22881-35-2;
PubChem CID	3326;
ChemSpider	3209;
UNII	HN0NCX453C;
ChEMBL	ChEMBL1475693;
CompTox Dashboard (EPA)	DTXSID3045435 ;
ECHA InfoCard	100.041.153
Chemical and physical data
Formula	C24H31N3O
Molar mass	377.532 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C2\C(=C(/N(N2c1ccccc1)C)CN(C(C)Cc3ccccc3)C)C(C)C;

Famprofazone (Gewodin, Gewolen) is a nonsteroidal anti-inflammatory agent (NSAID) of the pyrazolone series which is available over-the-counter in some countries such as Taiwan.^[1]^[2]^[3] It has analgesic, anti-inflammatory, and antipyretic effects.^[1]^[2] Famprofazone has been known to produce methamphetamine as an active metabolite, with 15–20% of an oral dose being converted to it.^[4]^[5] As a result, famprofazone has occasionally been implicated in causing positives on drug tests for amphetamines.^[3]

References

Clinical data

Routes of administration	Oral
ATC code	none
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 1-methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-4-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one
CAS Number	22881-35-2
PubChem CID	3326
ChemSpider	3209
UNII	HN0NCX453C
ChEMBL	ChEMBL1475693
CompTox Dashboard (EPA)	DTXSID3045435
ECHA InfoCard	100.041.153
Chemical and physical data
Formula	C₂₄H₃₁N₃O
Molar mass	377.532 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES O=C2\C(=C(/N(N2c1ccccc1)C)CN(C(C)Cc3ccccc3)C)C(C)C