Frunevetmab

Frunevetmab, sold under the brand name Solensia, is a monoclonal antibody used to treat pain associated with osteoarthritis in cats.[3] It is the first monoclonal antibody drug approved by the US Food and Drug Administration for animal use.[3] Frunevetmab is the international nonproprietary name.[5]

Frunevetmab
Monoclonal antibody
TypeWhole antibody
SourceRat
TargetNerve growth factor (NGF)
Clinical data
Trade namesSolensia
License data
Routes of
administration
Subcutaneous
ATCvet code
Legal status
Legal status
Identifiers
CAS Number
UNII
KEGG

Clinical usage

Frunevetmab is a cat-specific monoclonal antibody (a type of protein) designed to recognize and attach to a protein called nerve growth factor that is involved in the regulation of pain.[3] When frunevetmab binds to nerve growth factor, it prevents the pain signal from reaching the brain.[3]

Frunevetmab is indicated for the alleviation of pain associated with osteoarthritis in cats.[3][4]

The most common side effects seen in cats include vomiting, diarrhea, injection site pain, scabbing on the head and neck, dermatitis, and pruritus (itchy skin).[3]

History

In February 2021, frunevetmab was approved for medical use in the European Union.[4]

In January 2022, frunevetmab was approved for medical use in the United States.[3][6]

Development as a potential drug for humans was stopped due to risk concerns over worsening osteoarthritis.[7]

References

 This article incorporates public domain material from the United States Department of Health and Human Services

Bibliography


🔥 Top keywords: Main PageSpecial:SearchWikipedia:Featured picturesYasukeHarrison ButkerRobert FicoBridgertonCleopatraDeaths in 2024Joyce VincentXXXTentacionHank AdamsIt Ends with UsYouTubeNew Caledonia2024 Indian general electionHeeramandiDarren DutchyshenSlovakiaKingdom of the Planet of the ApesAttempted assassination of Robert FicoLawrence WongBaby ReindeerXXX: Return of Xander CageThelma HoustonFuriosa: A Mad Max SagaMegalopolis (film)Richard GaddKepler's SupernovaWicked (musical)Sunil ChhetriXXX (2002 film)Ashley MadisonAnya Taylor-JoyPlanet of the ApesNava MauYoung SheldonPortal:Current eventsX-Men '97