GSPT1

GSPT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3E1Y, 3J5Y, 4D61, 5HXB
Identifiers
Aliases	GSPT1, 551G9.2, ETF3A, GST1, eRF3a, G1 to S phase transition 1
External IDs	OMIM: 139259; MGI: 1316728; HomoloGene: 68226; GeneCards: GSPT1; OMA:GSPT1 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	11,916,082 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	11,072,189 bp
RNA expression pattern
	Top expressed in
	gingival epithelium; ; epithelium of colon; ; trabecular bone; ; islet of Langerhans; ; gastrocnemius muscle; ; ventricular zone; ; mucosa of sigmoid colon; ; blood; ; ganglionic eminence; ; parotid gland;
	Top expressed in
	abdominal wall; ; somite; ; primitive streak; ; dermis; ; morula; ; seminal vesicula; ; cervix; ; thymus; ; skin of back; ; yolk sac;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GTP binding; translation release factor activity; protein binding; GTPase activity; RNA binding;
Cellular component	translation release factor complex; intracellular anatomical structure; cytosol;
Biological process	G1 phase; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; protein biosynthesis; cytoplasmic translational termination; protein methylation; translational termination; G1/S transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	2935
	14852
	ENSG00000103342
	ENSMUSG00000062203
	P15170
	Q8R050
	NM_002094; NM_001130006; NM_001130007
	NM_001130008; NM_146066
	NP_001123478; NP_001123479; NP_002085
	NP_001123480; NP_666178
	Wikidata
View/Edit Human	View/Edit Mouse

Eukaryotic peptide chain release factor GTP-binding subunit ERF3A is an enzyme that in humans is encoded by the GSPT1 gene.^[5]^[6]^[7]

Interactions

GSPT1 has been shown to interact with BIRC2.^[8]

References

External links

Overview of all the structural information available in the PDB for UniProt: P15170 (Eukaryotic peptide chain release factor GTP-binding subunit ERF3A) at the PDBe-KB.

[5]

[6]

[7]

[1]

[2]

[3]

[4]

[8]

Search

GSPT1

Contents

Interactions

References

Further reading

External links