MIS12

Protein MIS12 homolog is a protein that in humans is encoded by the MIS12 gene.^[5][6][7]

MIS12
Identifiers
Aliases	MIS12, 2510025F08Rik, KNTC2AP, MTW1, hMis12, kinetochore complex component, MIS12 kinetochore complex component
External IDs	OMIM: 609178; MGI: 1914389; HomoloGene: 11429; GeneCards: MIS12; OMA:MIS12 - orthologs
Gene location (Human) Chr. Chromosome 17 (human)[1] Band 17p13.2 Start 5,486,285 bp[1] End 5,490,814 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 B4 Start 70,910,437 bp[2] End 70,918,197 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus epididymis germinal epithelium parietal pleura bronchial epithelial cell visceral pleura tibia superficial temporal artery palpebral conjunctiva caput epididymis appendix Top expressed in otic placode saccule maxillary prominence hand secondary oocyte yolk sac superior cervical ganglion somite thymus abdominal wall More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding Cellular component chromosome cytosol MIS12/MIND type complex chromosome, centromeric region nucleus kinetochore nuclear MIS12/MIND complex Biological process chromosome segregation cell division cell cycle kinetochore assembly attachment of mitotic spindle microtubules to kinetochore mitotic cell cycle protein localization to kinetochore mitotic sister chromatid segregation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79003 67139 Ensembl ENSG00000167842 ENSMUSG00000040599 UniProt Q9H081 Q9CY25 RefSeq (mRNA) NM_001258217 NM_001258218 NM_001258219 NM_001258220 NM_024039 NM_025993 RefSeq (protein) NP_001245146 NP_001245147 NP_001245148 NP_001245149 NP_076944 NP_080269 Location (UCSC) Chr 17: 5.49 – 5.49 Mb Chr 11: 70.91 – 70.92 Mb PubMed search [3] [4]
Wikidata
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