Mirodenafil

Mirodenafil belongs to the drug class PDE5 inhibitors, which includes avanafil, sildenafil, tadalafil, udenafil, and vardenafil, and is the first-line treatment for erectile dysfunction. Developed by SK Chemicals Life Science, mirodenafil is marketed in Korea under the trade name Mvix, offered both as tablets (50 mg and 100 mg) and as orally dissolving films (50 mg).

Mirodenafil
Legal status
Legal status
  • US: Unscheduled; not FDA-approved
  • Rx-only (KR)
Identifiers
  • 5-Ethyl-3,5-dihydro-2-[5-([4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl)-2-propoxyphenyl]-7-propyl-4H-pyrrolo[3,2-d]pyrimidin-4-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC26H37N5O5S
Molar mass531.67 g·mol−1
3D model (JSmol)
  • CCCc1cn(CC)c2c1[nH]c(nc2=O)c1c(OCCC)ccc(c1)S(=O)(=O)N1CCN(CC1)CCO
  • InChI=1S/C26H37N5O5S/c1-4-7-19-18-30(6-3)24-23(19)27-25(28-26(24)33)21-17-20(8-9-22(21)36-16-5-2)37(34,35)31-12-10-29(11-13-31)14-15-32/h8-9,17-18,32H,4-7,10-16H2,1-3H3,(H,27,28,33) ☒N
  • Key:MIJFNYMSCFYZNY-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Despite several clinical trials having been conducted,[1][2][3] mirodenafil has not been approved for use in the United States by the U.S. Food and Drug Administration.

References

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