Founded in 1939 as Genil Racing Club, the club changed its name to Puente Genil Balompié in 1941 and subsequently to CD Pontanés in 1950. It first reached the national competitions in 1955, playing in Tercera División and achieving immediate promotion after finishing fourth.
During the club's first season in Segunda División, it changed its name to Puente Genil CF. After suffering immediate relegation, the club also dropped a division in 1960 and folded in 1973.
In 1988 another Puente Genil CF was founded, after the merger of Puente Genil Industrial (founded in 1974) and CD Pontanés. The club played three seasons in the fourth category before being dissolved in 1995.
Puente Genil FC started to play in the regional leagues in 2000, and in 2010 the club changed its name to CD AD San Fermín. A partnership with cosmetics industry Salerm Cosmetics followed, and the club's name was changed officially to CD AD San Fermín Salerm Cosmetics. In 2018 the name was changed to Salerm Cosmetics Puente Genil FC mainly due to its previous history.
