SLC22A7

SLC22A7
Identifiers
Aliases	SLC22A7, NLT, OAT2, solute carrier family 22 member 7, hOAT11
External IDs	OMIM: 604995; MGI: 1859559; HomoloGene: 21328; GeneCards: SLC22A7; OMA:SLC22A7 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	43,305,538 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	46,749,383 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; kidney tubule; ; renal medulla; ; vena cava; ; olfactory bulb; ; glomerulus; ; metanephric glomerulus; ; human kidney; ; right testis; ; Skeletal muscle tissue of rectus abdominis;
	Top expressed in
	right kidney; ; human kidney; ; left lobe of liver; ; proximal tubule; ; embryo; ; embryo; ; morula; ; Convoluted tubule; ; proximal convoluted tubule; ; thymus;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	organic anion transmembrane transporter activity; protein binding; inorganic anion exchanger activity; sodium-independent organic anion transmembrane transporter activity;
Cellular component	integral component of membrane; plasma membrane; basolateral plasma membrane; integral component of plasma membrane; membrane;
Biological process	ion transport; organic anion transport; transmembrane transport; anion transmembrane transport; inorganic anion transport; sodium-independent organic anion transport;
	Sources:Amigo / QuickGO
Orthologs
	10864
	108114
	ENSG00000137204
	ENSMUSG00000067144
	Q9Y694; Q5T051
	Q91WU2
	NM_006672; NM_153320
	NM_144856
	NP_006663; NP_696961
	NP_659105
	Wikidata
View/Edit Human	View/Edit Mouse

Solute carrier family 22 member 7 is a protein that in humans is encoded by the gene SLC22A7.^[5]^[6]^[7]

The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described.^[7]

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles.^{[§ 1]}

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|alt=Fluorouracil (5-FU) Activity edit]]

Fluorouracil (5-FU) Activity edit

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SLC22A7

Contents

Interactive pathway map

See also

References

Further reading