SLITRK2

SLITRK2
Identifiers
Aliases	SLITRK2, CXorf2, SLITL1, SLIT and NTRK like family member 2, CXorf1, TMEM257
External IDs	OMIM: 300561 MGI: 2679449 HomoloGene: 13054 GeneCards: SLITRK2
Gene location (Human)
Chr.	X chromosome (human)
End	145,829,856 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	65,704,999 bp
RNA expression pattern
	Top expressed in
	internal globus pallidus; ; caudate nucleus; ; nucleus accumbens; ; ganglionic eminence; ; middle temporal gyrus; ; amygdala; ; putamen; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; prefrontal cortex;
	Top expressed in
	trigeminal ganglion; ; substantia nigra; ; Region I of hippocampus proper; ; dentate gyrus; ; subiculum; ; primary motor cortex; ; habenula; ; olfactory tubercle; ; hippocampus proper; ; cerebellar vermis;
	More reference expression data
	; ; ; ;
	More reference expression data
Orthologs
	84631
	245450
	ENSG00000185985
	ENSMUSG00000036790
	Q9H156
	Q810C0
NM_001144003; NM_001144004; NM_001144005; NM_001144006; NM_001144007;
	NM_001144008; NM_001144009; NM_001144010; NM_032539
	NM_001161431; NM_198863
NP_001137475; NP_001137476; NP_001137477; NP_001137478; NP_001137480;
	NP_001137481; NP_001137482; NP_115928
	NP_001154903; NP_942563
	Wikidata
View/Edit Human	View/Edit Mouse

SLIT and NTRK-like protein 2 is a protein that in humans is encoded by the SLITRK2 gene.^[5]^[6]^[7]

Function

Members of the SLITRK family, such as SLITRK2, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK2, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity.^[7]^[6]

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SLITRK2

Function

References

Further reading