In Toxoplasma gondii the translational repression of lactate dehydrogenase 1 (LDH1) was discovered to be mediated through its 5′UTR. A small nucleotide regulatory RNA hairpin was shown to be essential for the repression. It is possible that this hairpin may act as the nucleation site for the binding of a trans-acting factor(s) that allow for the translational repression.[1]
| LDH1 5′UTR | |
|---|---|
 Predicted secondary structure and sequence conservation of LDH1 5′UTR | |
| Identifiers | |
| Rfam | RF02697 |
| Other data | |
| Domain(s) | Bacteria |
| GO | GO:0045182 |
| SO | SO:0005836,SO:0000204 |
| PDB structures | PDBe |