Transfluthrin

Transfluthrin is a fast-acting pyrethroid insecticide with low persistency. It has the molecular formula C15H12Cl2F4O2.

Transfluthrin
Names
Preferred IUPAC name
(2,3,5,6-Tetrafluorophenyl)methyl (1R,3S)-3-(2,2-dichloroethen-1-yl)-2,2-dimethylcyclopropane-1-carboxylate
Other names
– CA: (1R-trans)-(2,3,5,6-tetrafluorophenyl)methyl 3-(2,2-dichloroethenyl)-2,2- dimethylcyclopropanecarboxylate[1]
– Common name transfluthrin: E-ISO (published).
– Synonym: benfluthrin (Bayer), NAK 4455[1]
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard100.100.666 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C15H12Cl2F4O2/c1-15(2)7(3-10(16)17)11(15)14(22)23-5-6-12(20)8(18)4-9(19)13(6)21/h3-4,7,11H,5H2,1-2H3/t7-,11+/m1/s1 checkY
    Key: DDVNRFNDOPPVQJ-HQJQHLMTSA-N checkY
  • InChI=1/C15H12Cl2F4O2/c1-15(2)7(3-10(16)17)11(15)14(22)23-5-6-12(20)8(18)4-9(19)13(6)21/h3-4,7,11H,5H2,1-2H3/t7-,11+/m1/s1
    Key: DDVNRFNDOPPVQJ-HQJQHLMTBF
  • Cl/C(Cl)=C/[C@@H]2[C@@H](C(=O)OCc1c(F)c(F)cc(F)c1F)C2(C)C
Properties
C15H12Cl2F4O2
Molar mass371.15 g·mol−1
AppearanceColorless crystals
Density1.507 g/cm3 (23 °C)
Melting point32 °C (90 °F; 305 K)
Boiling point135 °C (275 °F; 408 K) at 0.1 mm Hg
~ 250 °C at 760 mm Hg
5.7×10−5 g/L = 57 μg/L
Solubility in hexane, isopropanol, toluene, dichloromethanevery soluble
Vapor pressureConflicting data: 1×10−4 Pa (20 °C; 15 μg/m3)[2]

or 9×10−4 Pa (20 °C)[1]

Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Transfluthrin can be used in the indoor environment against flies, mosquitoes, moths and cockroaches. It is a relatively volatile substance and acts as a contact and inhalation agent.[1][3]

Transfluthrin, if used contrary to product instructions, may cause symptoms of poisoning including nervousness, anxiety, tremor, convulsions, skin allergies, sneezing, running nose and irritation. Treatment depends on symptoms. No specific antidotes are known, but antihistamines may help to control any allergies.[4]

In experiments, transfluthrin was shown to kill 85 percent of mosquitos within one hour of exposure at concentrations below 0.3 μg/m3 (which was the detection limit) in air.[5] (The data suggests that transfluthrin is effective at these concentrations within much less than an hour of exposure.)

Various household transfluthrin products such as vaporizers and mosquito coils may result in concentrations of 15 μg/m3 to 40 μg/m3.[6] In the EU, the acceptable exposure level (AEL) for humans is 500 μg/m3.[6]

See also

References