Transformer (gene)

Transformer
Transformer
Identifiers
Organism	Drosophila melanogaster
Symbol	tra
Entrez	39849
RefSeq (mRNA)	NM_079390.3
RefSeq (Prot)	NP_524114.1
UniProt	P11596
Other data
Chromosome	3L: 16.59 - 16.59 Mb
Structures
Search for
Structures	Swiss-model
Domains	InterPro

Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Female-specific protein transformer
Female-specific protein transformer
Identifiers
Symbol	Tra
Pfam	PF06495
InterPro	IPR010519
Pfam
Available protein structures:
Pfam	structures / ECOD
PDB	RCSB PDB; PDBe; PDBj
PDBsum	structure summary

Transformer (tra) is a family of genes which regulate sex determination in insects such as flies.^[1]^[2] Among its effects, it (P11596) regulates differences between males and females in Drosophila fruit flies.^[3]

Transformer 2

Identifiers

Organism

Drosophila melanogaster

Symbol

tra2

Other data

2R: 14.6 - 14.6 Mb

Search for
Structures	Swiss-model
Domains	InterPro

The tra-2 gene (P19018) is needed for sexual differentiation in female fruit flies, and for spermatogenesis in the males. It is not in the same protein family as tra, but instead works together with it in the splicing enhancer complex.^[4]^[5]

References

[1]

[2]

[3]

[4]

[5]