U6atac minor spliceosomal RNA is a non-coding RNA which is an essential component of the minor U12-type spliceosome complex. The U12-type spliceosome is required for removal of the rarer class of eukaryotic introns (AT-AC, U12-type).[1]
| U6atac minor spliceosomal RNA | |
|---|---|
 Predicted secondary structure and sequence conservation of U6atac | |
| Identifiers | |
| Symbol | U6atac |
| Rfam | RF00619 |
| Other data | |
| RNA type | Gene; snRNA; splicing |
| Domain(s) | Eukaryota |
| GO | GO:0000355 GO:0000369 GO:0030622 GO:0030627 GO:0005691 |
| SO | SO:0000274 |
| PDB structures | PDBe |
U6atac snRNA is proposed to form a base-paired complex with another spliceosomal RNA U4atac via two stem loop regions. These interacting stem loops have been shown to be required for in vivo splicing.[2] U6atac is the functional analog of U6 spliceosomal RNA inthe major U2-type spliceosomal complex.[2]
References
- Shukla GC, Padgett RA (1999). "Conservation of functional features of U6atac and U12 snRNAs between vertebrates and higher plants". RNA. 5 (4): 525–538. doi:10.1017/S1355838299982213. PMC 1369779. PMID 10199569.