UBL5

Ubiquitin-like protein 5 is a protein that in humans is encoded by the UBL5 gene.^[5]

UBL5
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1P0R, 4PYU
Identifiers
Aliases	UBL5, HUB1, ubiquitin like 5
External IDs	OMIM: 606849; MGI: 1913427; HomoloGene: 83305; GeneCards: UBL5; OMA:UBL5 - orthologs
Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19p13.2 Start 9,827,892 bp[1] End 9,830,115 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A3 Start 20,642,878 bp[2] End 20,647,140 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in anterior pituitary right testis left testis right adrenal gland mucosa of transverse colon left adrenal cortex right adrenal cortex C1 segment anterior cingulate cortex monocyte Top expressed in choroid plexus of fourth ventricle interventricular septum corneal stroma ventricular zone cardiac muscle tissue of left ventricle yolk sac lip granulocyte zygote plantaris muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding protein tag Cellular component cytoplasm nucleus Biological process mRNA splicing, via spliceosome positive regulation of protein targeting to mitochondrion Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 59286 66177 Ensembl ENSG00000198258 ENSMUSG00000084786 UniProt Q9BZL1 Q9EPV8 RefSeq (mRNA) NM_024292 NM_001048241 NM_025401 NM_001310746 RefSeq (protein) NP_001041706 NP_077268 NP_001041706.1 NP_077268.1 NP_001297675 NP_079677 NP_001347954 NP_001347955 NP_001347956 Location (UCSC) Chr 19: 9.83 – 9.83 Mb Chr 9: 20.64 – 20.65 Mb PubMed search [3] [4]
Wikidata
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It has been shown that in C. elegans mitochondria treated to lower expression of certain electron transport chain proteins during the L3/L4 stage, its expression levels is higher leading to increased lifespans.^[6]

Ubiquitin-like proteins (UBLs) are thought to be reversible modulators of protein function rather than protein degraders like ubiquitin (MIM 191339).[supplied by OMIM]^[5]