UPP1

UPP1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3EUE, 3EUF, 3NBQ
Identifiers
Aliases	UPP1, UDRPASE, UP, UPASE, UPP, uridine phosphorylase 1
External IDs	OMIM: 191730 MGI: 1097668 HomoloGene: 2524 GeneCards: UPP1
Gene location (Human)
Chr.	Chromosome 7 (human)
End	48,108,736 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	9,086,170 bp
RNA expression pattern
	Top expressed in
	upper lobe of left lung; ; monocyte; ; blood; ; right lung; ; spleen; ; vagina; ; cingulate gyrus; ; ascending aorta; ; amniotic fluid; ; anterior pituitary;
	Top expressed in
	jejunum; ; duodenum; ; conjunctival fornix; ; left colon; ; corneal stroma; ; mucous cell of stomach; ; placenta; ; primitive streak; ; epithelium of stomach; ; intestinal villus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; catalytic activity; pentosyltransferase activity; glycosyltransferase activity; uridine phosphorylase activity;
Cellular component	cytoplasm; cytosol; nucleus; nucleoplasm;
Biological process	pyrimidine nucleoside salvage; pyrimidine nucleotide metabolic process; nucleoside metabolic process; uridine metabolic process; nucleotide catabolic process; cellular response to glucose starvation; nucleobase-containing compound metabolic process; pyrimidine nucleoside catabolic process; UMP salvage; uridine catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	7378
	22271
	ENSG00000183696
	ENSMUSG00000020407
	Q16831
	P52624
NM_001287426; NM_001287428; NM_001287429; NM_001287430; NM_003364;
	NM_181597; NM_001362774
	NM_001159401; NM_001159402; NM_009477
NP_001274355; NP_001274357; NP_001274358; NP_001274359; NP_003355;
	NP_001349703
	NP_001152873; NP_001152874; NP_033503
	Wikidata
View/Edit Human	View/Edit Mouse

Uridine phosphorylase 1 is an enzyme that in humans is encoded by the UPP1 gene.^[5]^[6]^[7] It belongs to the uridine phosphorylase enzyme family.

Interactions

UPP1 has been shown to interact with Vimentin.^[8]

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles.^{[§ 1]}

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|alt=Fluorouracil (5-FU) Activity edit]]

Fluorouracil (5-FU) Activity edit

References

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human Uridine phosphorylase 1 (UPP1)

[5]

[6]

[7]

[1]

[2]

[3]

[4]

[8]

[§ 1]

Search

UPP1

Contents

Interactions

Interactive pathway map

References

Further reading

External links