Clinical data | |
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Trade names | Ztalmy |
Other names | GNX; CCD-1042; 3β-Methyl-5α-pregnan-3α-ol-20-one; 3α-Hydroxy-3β-methyl-5α-pregnan-20-one |
AHFS/Drugs.com | Monograph |
License data |
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Routes of administration | By mouth |
Drug class | Neurosteroid |
Legal status | |
Legal status | |
Identifiers | |
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Chemical and physical data | |
Formula | C22H36O2 |
Molar mass | 332.528 g·mol−1 |
3D model (JSmol) | |
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Ganaxolone, sold under the brand name Ztalmy, is a medication used to treat seizures in people with cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD).[1] It may be used in those who are at least 2 years old.[1] It is taken by mouth.[1]
Common side effects include sleepiness, fever, increased saliva, and seasonal allergies.[1] Other side effects may include suicidal thoughts.[1] It is a neuroactive steroid gamma-aminobutyric acid (GABA) A receptor positive modulator.[1]
Ganaxolone was approved for medical use in the United States in 2022.[1] It is an orphan drug in Europe and not approved in the United Kingdom as of 2022.[2] In the United States it costs about 133,000 USD for a person who is around 4.5 years old as of 2022.[2]
References
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