Ghemme is a comune in the Province of Novara in the Piedmont region in Italy. It is on the river Sesia about 80 kilometres (50 mi) northeast of Turin and about 25 kilometres (16 mi) northwest of Novara.
It is the birthplace of architect Alessandro Antonelli. The main sight is the castle (Castello-ricetto), which was built in the 11th to 15th centuries.