| Dato | Ritt | Vinner |
|---|
| 20.–26. feb. |  UAE Tour (2022) |  Tadej Pogačar (UAD)
Etapper: Philipsen, Cavendish, Bissegger (ITT), Pogačar, Philipsen, Vacek, Pogačar |
| 26. feb. |  Omloop Het Nieuwsblad (2022) | Wout van Aert (TJV) |
| 5. mar. |  Strade Bianche (2022) | Tadej Pogačar (UAD) |
| 6.–13. mar. |  Paris–Nice (2022) | Primož Roglič (TJV)
Etapper: Laporte, Jakobsen, Pedersen, van Aert (ITT), McNulty, Burgaudeau, Roglič, Yates |
| 7.–13. mar. | Tirreno–Adriatico (2022) | Tadej Pogačar (UAD)
Etapper: Ganna (ITT), Merlier, Ewan, Pogačar, Barguil, Pogačar, Bauhaus |
| 19. mar. | Milano–Sanremo (2022) | Matej Mohorič (TBV) |
| 21.–27. mar. |  Catalonia rundt (2022) |  Sergio Higuita (BOH)
Etapper: Matthews, Groves, O'Connor, Almeida, Vernon, Carapaz, Bagioli |
| 23. mar. | Tredagers i De Panne (2022) | Tim Merlier (AFC) |
| 25. mar. | E3 Saxo Bank Classic (2022) | Wout van Aert (TJV) |
| 27. mar. | Gent–Wevelgem (2022) |  Biniam Girmay (IWG) |
| 30. mar. | Dwars door Vlaanderen (2022) |  Mathieu van der Poel (AFC) |
| 3. apr. | Flandern rundt (2022) | Mathieu van der Poel (AFC) |
| 4.–9. apr. | Baskerland rundt (2022) | Daniel Martínez (IGD)
Etapper: Roglič (ITT), Alaphilippe, Bilbao, Martínez, Rodríguez, Izagirre |
| 10. apr. | Amstel Gold Race (2022) |  Michał Kwiatkowski (IGD) |
| 17. apr. | Paris–Roubaix (2022) | Dylan van Baarle (IGD) |
| 20. apr. | La Flèche Wallonne (2022) | Dylan Teuns (TBV) |
| 24. apr. | Liège–Bastogne–Liège (2022) | Remco Evenepoel (QST) |
| 26. apr.–1. mai |  Romandie rundt (2022) |  Aleksandr Vlasov (BOH)
Etapper: Hayter (ITT), Teuns, Hayter, Bevin, Higuita, Vlasov |
| 1. mai |  Eschborn-Frankfurt (2022) |  Sam Bennett (BOH) |
| 7.–29. mai | Giro d’Italia (2022) |  Jai Hindley (BOH)
Etapper: van der Poel, Yates (ITT), Cavendish, Kämna, Démare, Démare, Bouwman, De Gendt, Hindley, Girmay, Dainese, Oldani, Démare, Yates, Ciccone, Hirt, Buitrago, De Bondt, Bouwman, Covi, Sobrero (ITT) |
| 5.–12. juni | Critérium du Dauphiné (2022) | Primož Roglič (TJV)
Etapper: van Aert, Vuillermoz, Gaudu, Ganna (ITT), van Aert, Ferron, Verona, Vingegaard |
| 12.–19. juni | Sveits rundt (2022) |  Geraint Thomas (IGD)
Etapper: Williams, Leknessund, Sagan, Impey, Vlasov, Denz, Pinot, Evenepoel (ITT) |
| 1. – 24. juli | Tour de France (2022) |  Jonas Vingegaard (TJV)
Etapper:Lampaert (ITT), Jakobsen, Groenewegen, van Aert, Clarke, Pogačar, Pogačar, van Aert, Jungels, Cort, Vingegaard, Pidcock, Pedersen, Matthews, Philipsen, Houle, Pogačar, Vingegaard, Laporte, van Aert (ITT), Philipsen |
| 30. juli | Clásica de San Sebastián (2022) | Remco Evenepoel (QST) |
| 30. juli–5. aug. | Polen rundt (2022) | Ethan Hayter (IGD)
Etapper: Kooij, Thijssen, Higuita, Ackermann, Bauhaus, Arensman (ITT), Démare |
| 7.–13. aug. |  Benelux Tour | Avlyst[2] |
| 19. aug.–11. sep. | Vuelta a España (2022) | Remco Evenepoel (QST)
Etapper: Jumbo-Visma, Bennett, Bennett, Roglič, Soler, Vine, Herrada, Vine, Meintjes, Evenepoel (ITT), Groves, Carapaz, Pedersen, Carapaz, Arensman, Pedersen, Urán, Evenepoel, Pedersen, Carapaz, Molano |
| 21. aug. | Cyclassics Hamburg (2022) |  Marco Haller (BOH) |
| 28. aug. | Bretagne Classic Ouest-France (2022) | Wout van Aert (TJV) |
| 9. sep. |  Grand Prix Cycliste de Québec (2022) | Benoît Cosnefroy (ACT) |
| 11. sep. | Grand Prix Cycliste de Montréal (2022) | Tadej Pogačar (UAD) |
| 8. okt. | Il Lombardia (2022) | Tadej Pogačar (UAD) |
| 13.–18. okt. |  Tour of Guangxi | Avlyst[3] |
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