Umdlavuza wesibunu
Umdlavuza Vulvar kuyinto umdlavuza we ngemomozi, ingxenye engaphandle ye-umthondo zesifazane.Ngokuvamile kuthinta i- labia majora.Ngaphansi kakhulu, i- labia minora, i- clitoris, noma izindlala zangasese.Izimpawu zifaka phakathi isigaxa, ukulunywa, ukuguquka kwesikhumba, noma ukopha esithweni sangasese.
Izici zobungozi zibandakanya i- vulvar intraepithelial neoplasia (VIN), ukutheleleka nge-HPV, izinsumpa zangasese, ukubhema, nabalingani abaningi bezocansiIningi lomdlavuza we-vulvar ngama- squamous cell cancer .Ezinye izinhlobo zifaka i- adenocarcinoma, i- melanoma, i- sarcoma, ne- basal cell carcinoma.Ukuxilongwa kusolwa ngokususelwa ekuhlolweni komzimba futhi kuqinisekiswe yi- tissue biopsy.Ukuhlolwa kwansuku zonke akunconyiwe. [1]
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Izimpawu nezimpawu zingafaka:
- Ukulunywa, ukushiswa, noma ukopha esithweni sangasese esingapheli.
- Izinguquko kumbala wesikhumba se-vulva, ukuze zibukeke zibomvu noma zimhlophe kunokujwayelekile.
- Isikhumba siyashintsha esithweni sangasese, kufaka phakathi okubukeka njengokuqubuka noma izinsumpa.
- Izilonda, izigaxa noma izilonda esithweni sangasese ezingapheli.
- Ubuhlungu okhalweni, ikakhulukazi ngesikhathi sokuchama noma socansi .
Izimbangela
Izindlela ezimbili eziyinhloko ze-pathophysiological njengamanje ziyaqondakala ukuthi zifaka isandla ekwakhiweni komdlavuza we-vulvar-ukutheleleka kwe-human papillomavirus (HPV) nokuvuvukala okungapheli noma i-autoimmunity ethinta indawo ye-vulvar. [2] [3] [4]
Izimo ezihlala njalo zokuvuvukala kwesitho sangasese esingahle sibe yisandulela somdlavuza we-vulvar zifaka i- lichen sclerosus, engahle ihlukanise i-VIN ehlukile. [5] [6]
Izici zobungozi
Izici zobungozi zomdlavuza we-vulvar zihlobene kakhulu nezindlela eziyimbangela engenhla, ezibandakanya ukuvezwa noma ukutheleleka ngegciwane le-HPV kanye / noma ukutholwa noma ukuzitholela okuzenzakalelayo okuzenzakalelayo. [7] [8]
- Ukukhula kweminyaka
- Umlando we-vulvar noma i-neoplasia yomlomo wesibeletho
- Inani elandayo labalingani bobulili besilisa
- Umlando wangaphambi kokuhlasela noma umdlavuza womlomo wesibeletho
- Umlando wokubhema ugwayi
- Ukutheleleka nge-human immunodeficiency virus (HIV)
- IVulvar lichen sclerosus
- Ama-syndromes we-immunodeficiency
- Okhokho baseNyakatho Yurophu
Izinhlobo
Ngokuya ngemvelaphi yeselula, kungavela izinhlobo ezingaphansi komdlavuza we-histologic ezinhlakeni ze-vulvar. [9]
Ukwelashwa
Ukuhlinzwa kungumgogodla wokwelashwa ngokuya ngesiteji se-anatomical futhi imvamisa kugcinelwa umdlavuza ongakaze usabalale ngale kwe-vulva.Ukuhlinzwa kungabandakanya ukusikeka kwendawo okubanzi (ukusikwa kwesimila ngomkhawulo wokuphepha wezicubu ezinempilo, okuqinisekisa ukususwa ngokuphelele kwesimila), i- radical vulvectomy, noma i-vulvectomy ephelele ngokususa izicubu ze-vulvar, ama- lymph node angama- inguinal kanye nawesifazane. [9] [10] Ezimweni zomdlavuza wokuqala we-vulvar, ukuhlinzwa kungaba kuncane kakhulu futhi kuqukethe ukusikwa okubanzi noma i-vulvectomy elula.Ukuhlinzwa kukhulu kakhulu lapho umdlavuza ususakazekele ezithweni eziseduze njenge-urethra, isitho sangasese, noma i-rectum.Izinkinga zokuhlinzwa zifaka ukutheleleka kwesilonda, ukungasebenzi kocansi, i- edema ne- thrombosis, kanye ne- lymphedema yesibili kuya kuma-lymph node. [11]
I-Epidemiology
Umdlavuza weVulvar usanda kuthinta abantu ababalelwa ku-44,200 futhi kwaholela ekufeni kwabantu abayi-15,200 emhlabeni jikelele ngonyaka ka-2018.
Umdlavuza we-Vulvar ungahlukaniswa ube izinhlobo ezimbili.Omunye uqala njengokutheleleka nge-papillomavirus yomuntu, okuholela ku-vulvar intraepithelial neoplasia (VIN) futhi okungahle kube nomdlavuza we-vulvar. [12]Lokhu kuvame kakhulu kwabesifazane abasebasha, ikakhulu abangaphansi kweminyaka engama-40. [12]Uhlobo lwesibili yi-vulvar non-neoplastic epithelial disorders (VNED).Lokhu kuvame kakhulu kwabesifazane asebekhulile, ngenxa yengozi eyengeziwe yokuthuthukisa i-atypia yeselula nayo eholela kumdlavuza. [12]
eMelika
E-United States, isanda kwenzeka kubantu ababalelwa ku-6 070 ngokufa kwabantu abangu-1 280 ngonyaka.Kwenza cishe i-0.3% yamacala amasha womdlavuza, [13] no-5% womdlavuza we-gynecologic e-United States.Amacala omdlavuza we-Vulvar abelokhu ekhuphuka e-United States ngokunyuka kwama-.6% unyaka ngamunye kule minyaka eyishumi edlule.
Izixhumanisi zangaphandle
- IVulvar Cancer Treatment (PDQ®) –Health Professional Version —Imininingwane evela e-US National Cancer Institute
- "Vulvar cancer". American Family Physician 66 (7): 1269–74. October 2002. PMID 12387439. https://www.aafp.org/afp/2002/1001/p1269.html. Buyekeza i-athikili yabasebenzi abajwayelekile.
