6,6-Difluoronorethisterone

6,6-Difluoronorethisterone
Clinical data
Other names	6,6-Difluoro-17α-ethynyl-19-nortestosterone; 6,6-Difluoro-17α-ethynylestr-4-en-17β-ol-3-one
Identifiers
	IUPAC name (1S,2R,10R,11S,14S,15S)-14-Ethynyl-8,8-difluoro-14-hydroxy-15-methyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one;
CAS Number	25450-33-3;
Chemical and physical data
Formula	C20H24F2O2
Molar mass	334.407 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@]12CC[C@H]3[C@@H](CC(F)(F)C4=CC(=O)CC[C@H]34)[C@@H]1CC[C@]2(O)C#C;
	InChI InChI=1S/C20H24F2O2/c1-3-19(24)9-7-16-15-11-20(21,22)17-10-12(23)4-5-14(17)13(15)6-8-18(16,19)2/h1,10,13-16,24H,4-9,11H2,2H3/t13-,14-,15-,16+,18?,19-/m1/s1; Key:ZNTYQLFNPTXSPS-ZBWOJIPPSA-N;

6,6-Difluoronorethisterone, also known as 6,6-difluoro-17α-ethynyl-19-nortestosterone or as 6,6-difluoro-17α-ethynylestr-4-en-17β-ol-3-one, is a steroidal progestin of the 19-nortestosterone group that was described in 1971 but was never marketed.^[1]^[2]^[3] It is a fluorinated derivative of norethisterone. The C17β acetate ester, 6,6-difluoronorethisterone acetate, has also been synthesized and described.^[1]

References