Diflorasone

Diflorasone
Clinical data
Other names	6α,9α-Difluoro-16β-methylprednisolone; 6α,9α-Difluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione
Drug class	Corticosteroid; Glucocorticoid
Identifiers
	IUPAC name (6S,8S,9R,10S,11S,13S,14S,16S,17R)-6,9-Difluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;
CAS Number	2557-49-5;
PubChem CID	71415;
ChemSpider	64505;
UNII	T2DHJ9645W;
ECHA InfoCard	100.018.069
Chemical and physical data
Formula	C22H28F2O5
Molar mass	410.458 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C[C@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C)F;
	InChI InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13-,14-,16-,17-,19-,20-,21-,22-/m0/s1; Key:WXURHACBFYSXBI-XHIJKXOTSA-N;

Diflorasone is a synthetic glucocorticoid corticosteroid which was never marketed.^[1]^[2] A diacetate ester of diflorasone, diflorasone diacetate, in contrast, has been marketed.^[1]^[2]

References