Isurus

Although fossil teeth of Isurus have been reported from as early as the Late Cretaceous,^[5][6] they are likely to be of a shark with a similar dentition, Cretoxyrhina; since at one point they were considered to be the same (now defunct) genus Oxyrhina,^[7] and modern referrals to Isurus in the Cretaceous are scant. The earliest appearance of Isurus proper seems to be during the Oligocene with Isurus desori.^[8][9]

There has been much debate and speculation about the evolutionary origin and relationships between Isurus and its closest relatives, including the extant great white shark (Carcharodon carcharias). Molecular clock analyses place the last common ancestor of Isurus and Carcharodon between 43-60 million years ago during the Late Paleocene-Early Eocene.^[10] This insight should guide efforts to better resolve the fossil ancestry of both lineages, by providing a window of time in which to search for ancestor candidates.

Many fossil species of Lamnids have historically been placed under Isurus, which are now largely considered separate genera. These include species of Carcharodon (Cosmopolitodus) like C. hastalis, C. planus,^[11] species of Macrorhizodus,^[12][13] Isurolamna,^[14][15] and others.

The two living species are the shortfin mako shark (I. oxyrinchus) and the longfin mako shark (I. paucus). They range in length from 2.5 to 4.5 m (8.2 to 14.8 ft)^{[citation needed]}, and have an approximate maximum weight of 680 kg (1,500 lb)^{[citation needed]}. They both have a distinctive blue-gray color scheme common among mackerel sharks.

The genus contains these species:^[16]

• Shortfin mako shark
• Longfin mako shark
• White sharks
• List of prehistoric cartilaginous fish
• Shark meat