In 2017, Isaac possibly became the first Latino actor to play Hamlet in a major US production after he was cast in the Public Theater's Hamlet.[12] Isaac's work in 2018 included roles in the science fiction film Annihilation and the historical drama Operation Finale, the latter of which he also produced. He then reunited with A Most Violent Year director J. C. Chandor in the action adventure film Triple Frontier (2019).[13] Two years later, he starred in the science fiction film Dune, the drama The Card Counter and the HBO miniseries Scenes from a Marriage. The lattermost garnered him a nomination for a Golden Globe Award for Best Actor – Miniseries or Television Film. In 2022, Isaac joined the Marvel Cinematic Universe by playing the titular superheroes in the miniseries Moon Knight, for which he was nominated for a MTV Movie Award for Best Hero; he also served as an executive producer for the show.
Berg, Charles Ramírez (2018). "Oscar Isaac in A Most Violent Year". In Pomerance, Murray; Stevens, Kyle (eds.). Close-up: Great Cinematic Performances. Volume 1, American. Edinburgh University Press. pp. 291–301. ISBN978-1-474417-01-3.