Norgestomet, or norgestamet, sold under the brand name Syncro-Mate B and Crestar, is a progestin medication which is used in veterinary medicine to control estrus and ovulation in cattle.[1][2]
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| Clinical data | |
|---|---|
| Trade names | Syncro-Mate B, Crestar |
| Other names | Norgestamet; SC-21009; 11β-Methyl-17α-acetoxy-19-norprogesterone; 17α-Hydroxy-11β-methyl-19-norpregn-4-ene-3,20-dione acetate |
| Drug class | Progestogen; Progestin; Progestogen ester |
| Identifiers | |
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| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.042.359 |
| Chemical and physical data | |
| Formula | C23H32O4 |
| Molar mass | 372.505 g·mol−1 |
| 3D model (JSmol) | |
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Uses
Veterinary
Norgestomet is used in veterinary medicine.
Pharmacology
Pharmacodynamics
Norgestomet is a progestogen. In addition to the progesterone receptor, it possesses weak (micromolar) affinity for the glucocorticoid receptor.[3]
Chemistry
Norgestomet, also known as 11β-methyl-17α-acetoxy-19-norprogesterone or as 17α-hydroxy-11β-methyl-19-norpregn-4-ene-3,20-dione acetate, is a synthetic norpregnane steroid and a derivative of progesterone.[1][4]
History
Norgestomet was developed and introduced for veterinary use in the mid-1970s.[5]
Society and culture
Generic names
Norgestomet is the generic name of the drug and its INN, USAN, and BAN.[1][4] It also known as norgestamet and is known by its developmental code name SC-21009.[1][4][6]
Brand names
Norgestomet is marketed under the brand names Syncro-Mate B and Crestar.[1][4]