RacCS203 is a bat-derived strain of severe acute respiratory syndrome–related coronavirus collected in acuminate horseshoe bats from sites in Thailand and sequenced by Lin-Fa Wang's team. It has 91.5% sequence similarity to SARS-CoV-2 and is most related to the RmYN02 strain. Its spike protein is closely related to RmYN02's spike, both highly divergent from SARS-CoV-2's spike.[1][2]
| RacCS203 | |
|---|---|
Virus classification  | |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Pisuviricota |
| Class: | Pisoniviricetes |
| Order: | Nidovirales |
| Family: | Coronaviridae |
| Genus: | Betacoronavirus |
| Subgenus: | Sarbecovirus |
| Species: | |
| Strain: | RacCS203 |
Phylogenetics
Phylogenetic tree
A phylogenetic tree based on whole-genome sequences of SARS-CoV-2 and related coronaviruses is:[3][4]
| SARS‑CoV‑2 related coronavirus |
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
SARS-CoV-1, 79% to SARS-CoV-2 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Genome comparison
| SARS-CoV-2 compared to other SARSr-CoV (by nucleotide %)[13] | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Strain | Full-length genome | ORF1ab | S | RBM | ORF3a | E | M | ORF6 | ORF7a | ORF7b | ORF8 | N | ORF10 |
| RaTG13 | 96.10% | 96.50% | 92.30% | 86.30% | 96.30% | 99.60% | 95.50% | 98.40% | 95.60% | 99.20% | 97.00% | 96.90% | 99.20% |
| RmYN02 | 93.60% | 97.10% | 72.50% | 61.90% | 96.40% | 98.70% | 94.80% | 96.80% | 96.20% | 91.00% | 48.70% | 97.30% | 99.20% |
| RacCS203 | 91.50% | 94.30% | 71.30% | 61.60% | 91.90% | 99.10% | 94.60% | 96.20% | 92.40% | 93.90% | 91.60% | 93.20% | 99.20% |
| GD/1/2019 | 90.20% | 90.20% | 83.70% | 86.90% | 93.20% | 99.10% | 93.30% | 95.70% | 93.40% | 91.70% | 92.10% | 96.20% | 99.20% |
| SL-ZC45 | 87.70% | 89.00% | 75.50% | 62.50% | 87.80% | 98.70% | 93.40% | 94.60% | 88.80% | 94.70% | 88.50% | 91.10% | 99.20% |
| SL-ZXC21 | 87.50% | 88.70% | 74.90% | 61.60% | 88.90% | 98.70% | 93.40% | 94.60% | 89.10% | 95.50% | 88.50% | 91.20% | 99.20% |
| GX-P4L | 85.40% | 84.80% | 83.60% | 80.00% | 86.80% | 97.40% | 91.30% | 90.90% | 86.60% | 83.50% | 81.30% | 91.00% | 88.90% |
| GX-P5L | 85.20% | 84.60% | 83.30% | 79.90% | 87.00% | 97.40% | 91.30% | 90.90% | 86.40% | 83.50% | 80.70% | 91.00% | 94.00% |
| SARS-CoV | 79.30% | 79.70% | 72.30% | 71.90% | 75.30% | 93.50% | 85.50% | 75.50% | 82.10% | 83.80% | 45.80% | 88.20% | 93.20% |
| Rc-o319 | 79.20% | 79.80% | 72.20% | 70.10% | 83.30% | 97.40% | 86.60% | 86.60% | 78.40% | 77.30% | 52.30% | 88.30% | 94.90% |
| SARS-CoV-2 compared to other SARSr-CoV (by amino acid %)[13] | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Strain | Full-length genome | ORF1ab | S | RBM | ORF3a | E | M | ORF6 | ORF7a | ORF7b | ORF8 | N | ORF10 |
| RaTG13 | 98.50% | 97.30% | 90.10% | 97.80% | 100.00% | 99.60% | 100.00% | 97.50% | 97.70% | 95.00% | 99.10% | 97.40% | |
| RmYN02 | 98.80% | 72.40% | 63.20% | 96.70% | 100.00% | 98.70% | 96.70% | 95.90% | 83.70% | 28.20% | 98.60% | 97.40% | |
| RacCS203 | 97.30% | 72.30% | 63.70% | 97.50% | 100.00% | 99.10% | 98.40% | 95.90% | 93.00% | 94.20% | 95.70% | - | |
| GD/1/2019 | 96.70% | 90.00% | 96.90% | 97.10% | 100.00% | 98.70% | 96.70% | 97.50% | 95.40% | 95.00% | 97.90% | 97.40% | |
| SL-ZC45 | 95.60% | 80.20% | 65.90% | 90.90% | 100.00% | 98.70% | 93.40% | 87.60% | 93.00% | 94.20% | 94.30% | 97.40% | |
| SL-ZXC21 | 95.20% | 79.70% | 65.90% | 92.00% | 100.00% | 98.70% | 93.40% | 88.40% | 93.00% | 94.20% | 94.30% | - | |
| GX-P4L | 92.50% | 92.30% | 86.60% | 89.50% | 100.00% | 98.20% | 95.10% | 88.40% | - | 87.60% | 93.60% | 73.70% | |
| GX-P5L | 92.50% | 92.40% | 86.60% | 89.80% | 100.00% | 98.20% | 95.10% | 88.40% | 72.10% | 87.60% | 93.80% | 84.20% | |
| SARS-CoV | 86.10% | 75.80% | 73.10% | 72.40% | 94.70% | 90.50% | 67.20% | 85.30% | 81.40% | - | 90.50% | 81.60% | |
| Rc-o319 | 87.60% | 76.20% | 73.50% | 87.00% | 98.70% | 91.00% | 83.60% | 73.80% | 69.80% | 26.80% | 89.50% | 86.80% | |