Toxoplasma

obligate intracellular parasitic protozoan that causes toxoplasmosis

Toxoplasma gondii is a protozoan parasite that can infect almost all warm-blooded animals, including humans.[1][2]

Toxoplasma gondii
T. gondii tachyzoites
Scientific classification
Kingdom:
Phylum:
Class:
Subclass:
Order:
Eucoccidiorida
Family:
Sarcocystidae
Genus:
Toxoplasma
Binomial name
Toxoplasma gondii

In humans, it is one of the most common parasites.[3] Blood test show that up to a third of the world population has been or is infected with T. gondii. Infection rates differ greatly from country to country.[4]

Although mild, flu-like symptoms occasionally occur during the first few weeks, infection with T. gondii generally produces no symptoms in healthy human adults.[5] But in infants, HIV/AIDS patients, and others with weakened immunity, infection can cause serious and occasionally fatal illness (toxoplasmosis).[2][5]p77

Infection in humans and other warm-blooded animals can occur

  1. by eating raw or undercooked meat containing T. gondii tissue cysts.[6][7]
  2. by drinking water or eating anything contaminated with oocysts.[8] in the faeces of an infected animal.[7]
  3. from a blood transfusion or organ transplant
  4. or by transmission from mother to foetus across the placenta.[7]

The parasite can only sexually reproduce in the intestines of members of the cat family (felids).[9] Felids are therefore the definitive hosts of T. gondii, with all other hosts defined as 'intermediate hosts'.

References