SARS-CoV-2 Lambda variant

The Lambda variant, also known as lineage C.37, is a variant of SARS-CoV-2, the virus that causes COVID-19.[1] It was first detected in Peru in August 2020.[2] On 14 June 2021, the World Health Organization (WHO) named it Lambda variant[1] and designated it as a variant of interest.[3] It has spread to at least 30 countries[4] around the world and is known to be more resistant to neutralizing antibodies compared to other strains.[5][6][7] There is evidence that suggests the Lambda variant is both more infectious and resistant to vaccines than the Alpha and/or Gamma variant.[8][9]

Mutations

The Lambda genome has the following amino acid mutations, all of which are in the virus's spike protein code: G75V, T76I, Δ246-252, L452Q, F490S, D614G and T859N.[10]

History

First samples of the Lambda variant were detected in Peru in August 2020[2] and by April 2021, over eighty percent of new cases of COVID-19 in Peru were from the new variant.[1][12] In mid-June 2021, 90.6% of new COVID-19 cases in Arequipa and 78.1% of new cases in Cusco were the Lambda variant, according to the Peruvian Ministry of Health.[13] By this time the Lambda variant had also spread throughout South America and was detected in twenty-nine countries in total, especially in Argentina, Chile and Ecuador.[12][14] The WHO designated the Lambda variant as a "variant of interest" on 14 June 2021.[1]

On 6 July 2021, Australia reported its first case of the Lambda variant in an overseas traveler who had been in a New South Wales quarantine hotel in April.[15]

On 19 July 2021, Texas reported its first case of the Lambda variant.[16] On 22 July 2021, Florida reported 126 cumulative confirmed cases of the Lambda variant.[17] On 28 July 2021, University of Miami researchers announced random sampling showed 3 percent of COVID-19 patients in Jackson Memorial Health System and at University of Miami's UHealth Tower were infected with it.[18] On 5 August 2021, Louisiana reported its first case of the Lambda variant.[19]

On 7 August 2021, Japan confirmed its first case of the Lambda variant, with the infected person arriving in Japan from Peru on 20 July.[20]

On 15 August 2021, the Philippines confirmed its first case of the Lambda variant.[21]

Statistics

Cases by country (Updated as of 23 August 2021) GISAID[22]
CountryConfirmed casesCollection date
 Chile1,48913 July 2021
 Peru1,48015 June 2021
 United States8485 August 2021
 Ecuador19420 July 2021
 Mexico18914 July 2021
 Spain1247 July 2021
 Argentina11124 June 2021
 Germany8713 July 2021
 France5619 July 2021
 Colombia5129 June 2021
 Israel259 May 2021
  Switzerland825 July 2021
 Canada2621 June 2021
 The Netherlands311 July 2021
 Saint Kitts and Nevis106 June 2021
 Belgium223 July 2021
 United Kingdom810 July 2021
 Italy1226 June 2021
 Brazil721 June 2021
 India612 April 2021
 Denmark111 August 2021
 Sweden115 July 2021
 South Africa314 July 2021
 Portugal110 June 2021
 Qatar313 April 2021
 Latvia230 April 2021
 Aruba22 June 2021
 Bolivia12 June 2021
 Uruguay115 April 2021
 Australia13 April 2021
 Lithuania119 May 2021
 Norway17 July 2021
 Estonia11 April 2021
 Russia121 March 2021
 Finland131 May 2021
 Turkey18 February 2021
 Bangladesh120 March 2021
 Japan17 August 2021
 Philippines115 August 2021[23]
 Venezuela25 May 2021
 Mayotte115 July 2021
 El Salvador330 April 2021
 Guatemala13 July 2021
 Costa Rica420 July 2021
 World (44 countries)Total: 4,763Total as of 23 August 2021

See also

References