Methamphetamine

Methamphetamine (contractit frae N-methylamphetamine) is a strang central nervish seestem (CNS) stimulant that is mainly uised as a recreational drog an less commonly as a treatment for attention deficit hyperactivity disorder an obesity.

Methamphetamine
INN: Metamfetamine

Clinical data
Pronunciation	/ˌmɛθæmˈfɛtəmiːn/
Tred names	Desoxyn
AHFS/Drugs.com	monograph
Leecence data	US FDA: Methamphetamine
Pregnancy category	US: C (Risk nae ruled oot)
Dependence liability	Pheesical: none Psychological: heich
Addiction liability	Heich
Routes o admeenistration	Medical: oral (ingestion), intravenous[1] Recreational: oral, intravenous, intramuscular, subcutaneous, smeuk inhalation, insufflation, rectal, vaginal
ATC code	N06BA03 (WHO)
Legal status
Legal status	AU: S8 (Controlled) CA: Schedule I DE: Anlage II (Prohibitit) NZ: Class A UK: Cless A US: Schedule II UN: Psychotropic Schedule II
Pharmacokinetic data
Bioavailability	Oral: 70%[2] IV: 100%[2]
Protein bindin	Varies widely[3]
Metabolism	CYP2D6[4] and FMO3[5]
Onset o action	Rapid[6]
Biological hauf-life	5–30 oors[7]
Duration o action	10–20 oors[6]
Excretion	Primarily renal
Identifiers
IUPAC name (RS)-N-methyl-1-phenylpropan-2-amine
Synonyms	N-methylamphetamine, N,α-dimethylphenethylamine, desoxyephedrine
CAS Nummer	537-46-2 Y
PubChem CID	1206
IUPHAR/BPS	4803
DrugBank	DB01577 Y
ChemSpider	1169 Y
UNII	44RAL3456C
KEGG	D08187 Y
ChEBI	CHEBI:6809 Y
ChEMBL	CHEMBL1201201 Y
PDB ligand	B40 (PDBe, RCSB PDB)
ECHA InfoCard	100.007.882
Chemical and physical data
Formula	C10H15N
Molar mass	149.24 g·mol−1
3D model (Jmol)	Interactive eemage
Chirality	Racemic mixtur
Meltin pynt	3 °C (37 °F) (predicted)[8]
Bylin pynt	212 °C (414 °F) at 760 mmHg[9]
SMILES N(C(Cc1ccccc1)C)C
InChI InChI=1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3 Y Key:MYWUZJCMWCOHBA-UHFFFAOYSA-N Y
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