Major depressive disorder

Major depressive disorder (MDD), kent simply as depression, is a mental disorder chairacterised bi at least twa weeks o law muid that is present athort maist situations.^[1] It is eften accompanied bi law self-esteem, loss o interest in normally enjoyable activities, law energy, an pyne wioot a clear cause.^[1]

Major depressive disorder
Synonyms	Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression
Vincent van Gogh's 1890 pentin Sorraein auld man ('At Eternity's Gate')
Specialty	Psychiatry
Symptoms	Law muid, law sel-esteem, loss o interest in normally enjoyable activities, law energy, pyne withoot a clear cause[1]
Complications	Suicide[2]
Uisual onset	20s–30s[3][4]
Duration	> 2 weeks[1]
Causes	Genetic, environmental, an psychological factors[1]
Risk factors	Faimily history, major life cheenges, certain medications, chronic heal problems, substance abuiss[1][3]
Seemilar condeetions	Sadness[3]
Treatment	Coonselin, antidepressant medication, electroconvulsive therapy[1]
Frequency	216 million (2015)[5]
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